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1

Activation of cathepsin B, secreted by a colorectal cancer cell line requires low pH and is mediated by cathepsin D

Jos W. J. Van Der Stappen, Ann C. Williams, Rose A. Maciewicz, Christos Paraskeva

Journal:

International Journal of Cancer

Year:

1996

Language:

english

File:

PDF, 1010 KB

english, 1996

2

Self-reported adult footwear and the risks of lower limb osteoarthritis: the GOAL case control study

McWilliams, Daniel F, Muthuri, Stella, Muir, Kenneth R, Maciewicz, Rose A, Zhang, Weiya, Doherty, Michael

Journal:

BMC Musculoskeletal Disorders

Year:

2014

Language:

english

File:

PDF, 263 KB

english, 2014

3

Diurnal variation in the femoral articular cartilage of the knee in young adult humans

John C. Waterton, Stuart Solloway, John E. Foster, Michael C. Keen, Stephen Gandy, Brian J. Middleton, Rose A. Maciewicz, Iain Watt, Paul A. Dieppe, Christopher J. Taylor

Journal:

Magnetic Resonance in Medicine

Year:

2000

Language:

english

File:

PDF, 388 KB

english, 2000

4

Self-reported knee and foot alignments in early adult life and risk of osteoarthritis

Daniel F. McWilliams, Sally Doherty, Rose A. Maciewicz, Kenneth R. Muir, Weiya Zhang, Michael Doherty

Journal:

Arthritis Care & Research

Year:

2010

Language:

english

File:

PDF, 93 KB

english, 2010

5

Self-reported knee malalignment in early adult life as an independent risk for knee chondrocalcinosis

Abhishek Abhishek, Sally Doherty, Rose A. Maciewicz, Kenneth R. Muir, Weiya Zhang, Michael Doherty

Journal:

Arthritis Care & Research

Year:

2011

Language:

english

File:

PDF, 106 KB

english, 2011

6

Nonspherical femoral head shape (pistol grip deformity), neck shaft angle, and risk of hip osteoarthritis: A case–control study

Michael Doherty, Philip Courtney, Sally Doherty, Wendy Jenkins, Rose A. Maciewicz, Kenneth Muir, Weiya Zhang

Journal:

Arthritis & Rheumatism

Year:

2008

Language:

english

File:

PDF, 177 KB

english, 2008

7

Involvement of different risk factors in clinically severe large joint osteoarthritis according to the presence of hand interphalangeal nodes

Ana M. Valdes, Daniel McWilliams, Nigel K. Arden, Sally A. Doherty, Margaret Wheeler, Kenneth R. Muir, Weiya Zhang, Cyrus Cooper, Rose A. Maciewicz, Michael Doherty

Journal:

Arthritis & Rheumatism

Year:

2010

Language:

english

File:

PDF, 96 KB

english, 2010

8

Temporal relationship between serum adipokines, biomarkers of bone and cartilage turnover, and cartilage volume loss in a population with clinical knee osteoarthritis

Patricia A. Berry, Simon W. Jones, Flavia M. Cicuttini, Anita E. Wluka, Rose A. Maciewicz

Journal:

Arthritis & Rheumatism

Year:

2011

Language:

english

File:

PDF, 85 KB

english, 2011

9

Immunodetection of cathepsins b and l present in and secreted from human pre-malignant and malignant colorectal tumour cell lines

Rose A. Maciewicz, R. John Wardale, David J. Etherington, Christos Paraskeva

Journal:

International Journal of Cancer

Year:

1989

Language:

english

File:

PDF, 1.65 MB

english, 1989

10

Transmission densitometry of stained nitrocellulose paper

Rose A. Maciewicz, Peter J. Knight

Journal:

Analytical Biochemistry

Year:

1988

Language:

english

File:

PDF, 769 KB

english, 1988

11

Preclinical investigation of fibrodysplasia and its relevance to human musculo-skeletal syndrome

Michelle Coulson, Russell Westwood, Jonathan D. Tugwood, Rose A. Maciewicz, Jonathan Bowyer, Bob C. Scott

Journal:

Year:

2008

Language:

english

File:

PDF, 48 KB

english, 2008

12

Cathepsin L-deficient mice exhibit abnormal skin and bone development and show increased resistance to osteoporosis following ovariectomy

Wendy Potts, Jonathan Bowyer, Huw Jones, David Tucker, Anthony J. Freemont, Andrew Millest, Colin Martin, Wendy Vernon, Diane Neerunjun, Gillian Slynn, Fiona Harper, Rose Maciewicz

Journal:

International Journal of Experimental Pathology

Year:

2004

Language:

english

File:

PDF, 4.29 MB

english, 2004

13

Evaluation of a magnetic resonance biomarker of osteoarthritis disease progression: doxycycline slows tibial cartilage loss in the Dunkin Hartley guinea pig

Jonathan Bowyer, Chris G. Heapy, Joanne K. Flannelly, John C. Waterton, Rose A. Maciewicz

Journal:

International Journal of Experimental Pathology

Year:

2009

Language:

english

File:

PDF, 104 KB

english, 2009

14

Treatment with Soluble VEGF Receptor Reduces Disease Severity in Murine Collagen-Induced Arthritis

Miotla, Jadwiga, Maciewicz, Rose, Kendrew, Jane, Feldmann, Marc, Paleolog, Ewa

Journal:

Laboratory Investigation

Year:

2000

Language:

english

File:

PDF, 1.15 MB

english, 2000

15

Distribution of finger nodes and their association with underlying radiographic features of osteoarthritis

Frances Rees, Sally Doherty, Michelle Hui, Rose Maciewicz, Kenneth Muir, Weiya Zhang, Michael Doherty

Journal:

Arthritis Care & Research

Year:

2012

Language:

english

File:

PDF, 176 KB

english, 2012

16

Monoclonal antibodies to rabbit liver cathepsin B

R. John Wardale, Rose A. Maciewicz, David J. Etherington

Journal:

Bioscience Reports

Year:

1986

Language:

english

File:

PDF, 742 KB

english, 1986

17

Inverse Relationship Between Preoperative Radiographic Severity and Postoperative Pain in Patients with Osteoarthritis who Have Undergone Total Joint Arthroplasty

Ana M. Valdes, Sally A. Doherty, Weiya Zhang, Kenneth R. Muir, Rose A. Maciewicz, Michael Doherty

Journal:

Seminars in Arthritis and Rheumatism

Year:

2012

Language:

english

File:

PDF, 695 KB

english, 2012

18

Collagenolytic Cathepsins of Rabbit Spleen: A Kinetic Analysis of Collagen Degradation and Inhibition by Chicken Cystatin

Rose A. Maciewicz, David J. Etherington, Janko Kos, Vito Turk

Journal:

Collagen and Related Research

Year:

1987

Language:

english

File:

PDF, 671 KB

english, 1987

19

Susceptibility of the cartilage collagens types II, IX and XI to degradation by the cysteine proteinases, cathepsins B and L

Rose A. Maciewicz, Sandra F. Wotton, David J. Etherington, Victor C. Duance

Journal:

Year:

1990

Language:

english

File:

PDF, 868 KB

english, 1990

20

New α-Substituted Succinate-Based Hydroxamic Acids as TNFα Convertase Inhibitors

Barlaam, Bernard, Bird, T. Geoffrey, Lambert-van der Brempt, Christine, Campbell, Douglas, Foster, Steve J., Maciewicz, Rose

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 334 KB

english, 1999

21

Catalytic activity of ADAM28

Linda Howard, Yufang Zheng, Maureen Horrocks, Rose A. Maciewicz, Carl Blobel

Journal:

Year:

2001

Language:

english

File:

PDF, 280 KB

english, 2001

22

Chondrocalcinosis is common in the absence of knee involvement

Abhishek Abhishek, Sally Doherty, Rose Maciewicz…

Journal:

Arthritis Research & Therapy

Year:

2012

Language:

english

File:

PDF, 197 KB

english, 2012

23

The association betweenANKHpromoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study

Abhishek, Abhishek, Doherty, Sally, Maciewicz, Rose, Muir, Kenneth, Zhang, Weiya, Doherty, Michael, Valdes, Anna M

Journal:

Arthritis Research & Therapy

Year:

2014

Language:

english

File:

PDF, 209 KB

english, 2014

24

Gene-environment interaction between body mass index andtransforming growth factor beta 1(TGFβ1) gene in knee and hip osteoarthritis

Muthuri, Stella G, Doherty, Sally, Zhang, Weiya, Maciewicz, Rose A, Muir, Kenneth R, Doherty, Michael

Journal:

Arthritis Research & Therapy

Year:

2013

Language:

english

File:

PDF, 172 KB

english, 2013

25

Hydantoin based inhibitors of MMP13—Discovery of AZD6605

De Savi, Chris, Waterson, David, Pape, Andrew, Lamont, Scott, Hadley, Elma, Mills, Mark, Page, Ken M., Bowyer, Jonathan, Maciewicz, Rose A.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 2.81 MB

english, 2013

26

Degradation of myofibrils from rabbit, chicken and beef by cathepsin l and lysosomal lysates

Mikami, Masayuki, Whiting, Alan H., Taylor, Mark A.J., Maciewicz, Rose A., Etherington, David J.

Journal:

Year:

1987

Language:

english

File:

PDF, 1.57 MB

english, 1987

27

Effects of shearing on chromatin structure

Maciewicz, Rose A., Li, Hsueh Jei

Journal:

Year:

1978

Language:

english

File:

PDF, 701 KB

english, 1978

28

Lower Leptin/Adiponectin Ratio and Risk of Rapid Lung Function Decline in Chronic Obstructive Pulmonary Disease

Suzuki, Masaru, Makita, Hironi, Östling, Jörgen, Thomsen, Laura H., Konno, Satoshi, Nagai, Katsura, Shimizu, Kaoruko, Pedersen, Jesper H., Ashraf, Haseem, Bruijnzeel, Piet L. B., Maciewicz, Rose A., N

Journal:

Annals of the American Thoracic Society

Year:

2014

Language:

english

File:

PDF, 1.47 MB

english, 2014

29

Integrin α 5 β 1 and ADAM-17 Interact in Vitro and Co-localize in Migrating HeLa Cells

Bax, Daniel V., Messent, Anthea J., Tart, Jonathan, van Hoang, Mien, Kott, Jane, Maciewicz, Rose A., Humphries, Martin J.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 968 KB

english, 2004

30

Beer and wine consumption and risk of knee or hip osteoarthritis: a case control study

Muthuri, Stella G, Zhang, Weiya, Maciewicz, Rose A, Muir, Kenneth, Doherty, Michael

Journal:

Arthritis Research & Therapy

Year:

2015

Language:

english

File:

PDF, 429 KB

english, 2015

31

Structural transition in chromatin induced by ions in solution

Li, Hsueh Jei, Hu, Ali W., Maciewicz, Rose A., Cohen, Patricia, Santella, Regina M., Chang, Catherine

Journal:

Nucleic Acids Research

Year:

1977

Language:

english

File:

PDF, 628 KB

english, 1977

32

Cloning and characterization of ADAM28: evidence for autocatalytic pro-domain removal and for cell surface localization of mature ADAM28

HOWARD, Linda, MACIEWICZ, Rose A., BLOBEL, Carl P.

Journal:

Biochemical Journal

Year:

2000

Language:

english

File:

PDF, 255 KB

english, 2000

33

Cloning and characterization of ADAM28: evidence for autocatalytic pro-domain removal and for cell surface localization of mature ADAM28

HOWARD, Linda, MACIEWICZ, Rose A., BLOBEL, Carl P.

Journal:

Biochemical Journal

Year:

2000

Language:

english

File:

PDF, 255 KB

english, 2000

34

Enzyme immunoassay for cathepsins B and L in synovial fluids from patients with arthritis

MACIEWICZ, ROSE A., ETHERINGTON, DAVID J.

Journal:

Biochemical Society Transactions

Year:

1988

Language:

english

File:

PDF, 259 KB

english, 1988

35

Studies on the activation mechanism for the precursor to cathepsin L

MACIEWICZ, ROSE A., WARDALE, R. JOHN, ETHERINGTON, DAVID J.

Journal:

Biochemical Society Transactions

Year:

1988

Language:

english

File:

PDF, 243 KB

english, 1988

36

Effect of physiological pressure on the secretion of cysteine proteinases and their inhibitors from articular cartilage

MACIEWICZ, ROSE A., HALL, ANDREW C., URBAN, JILL P. G.

Journal:

Biochemical Society Transactions

Year:

1991

Language:

english

File:

PDF, 147 KB

english, 1991

37

Use of Neoepitope Antibodies to Study Membrane Processing of CD23

Wright, Tracey J., MacIewicz, Rose A., Hewitt, Colin R.A.

Journal:

Biochemical Society Transactions

Year:

1999

Language:

english

File:

PDF, 147 KB

english, 1999

38

Relationship between the secretion of cysteine proteinases and their inhibitors and malignant potential

van der STAPPEN, JOS W.J., PARASKEVA, CHRISTOS, WILLIAMS, ANN C., HAGUE, ANGELA, MACIEWICZ, ROSE A.

Journal:

Biochemical Society Transactions

Year:

1991

Language:

english

File:

PDF, 191 KB

english, 1991

39

Beta-blocker use associates with lower prevalence of joint pain and lower opioid requirement in people with osteoarthritis

Valdes, Ana M, Abhishek, Abhishek, Muir, Kenneth, Zhang, Weiya, Maciewicz, Rose A, Doherty, Michael

Journal:

Arthritis Care & Research

Year:

2016

Language:

english

File:

PDF, 726 KB

english, 2016

40

Phenotypic screening identifies Axl kinase as a negative regulator of an alveolar epithelial cell phenotype

Fujino, Naoya, Kubo, Hiroshi, Maciewicz, Rose A

Journal:

Laboratory Investigation

Year:

2017

Language:

english

File:

PDF, 5.20 MB

english, 2017

41

Evidence of changes to skeletal muscle contractile properties during the initiation of disease in the ageing guinea pig model of osteoarthritis

Daniel P Tonge,Ronald G Bardsley,Tim Parr,Rose A Maciewicz…

Journal:

Longevity & Healthspan

Year:

2013

Language:

english

File:

PDF, 453 KB

english, 2013

42

Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseases

Fujino, Naoya, Brand, Oliver J., Morgan, David J., Fujimori, Toshifumi, Grabiec, Aleksander M., Jagger, Christopher P., Maciewicz, Rose A., Yamada, Mitsuhiro, Itakura, Koji, Sugiura, Hisatoshi, Ichino

Journal:

Journal of Experimental Medicine

Year:

2019

Language:

english

File:

PDF, 4.09 MB

english, 2019

43

Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseases

Fujino, Naoya, Brand, Oliver J., Morgan, David J., Fujimori, Toshifumi, Grabiec, Aleksander M., Jagger, Christopher P., Maciewicz, Rose A., Yamada, Mitsuhiro, Itakura, Koji, Sugiura, Hisatoshi, Ichino

Journal:

Journal of Experimental Medicine

Year:

2019

File:

PDF, 4.09 MB

2019